STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepFHypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (144 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.968
EDS74391.1
S4 domain protein; COG: COG2302 Uncharacterized conserved protein, contains S4-like domain; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.948
EDS74392.1
Hypothetical protein; KEGG: lwe:lwe2040 1.0e-10 cell division protein DivIVA K01549; COG: COG3599 Cell division initiation protein; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.904
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
  
 
 0.843
EDS73962.1
Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.799
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
  
 0.694
EDS74070.1
Cell envelope-like function transcriptional attenuator common domain protein; COG: COG1316 Transcriptional regulator; Psort location: CytoplasmicMembrane, score: 7.63.
  
   
 0.657
EDS75520.1
Kinase domain protein; KEGG: lmo:lmo1820 5.3e-110 similar to putative serine/threonine-specific protein kinase K08884; COG: COG2815 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.49.
 
   
 0.652
EDS73958.1
Cell envelope-like function transcriptional attenuator common domain protein; COG: COG1316 Transcriptional regulator; Psort location: CytoplasmicMembrane, score: 9.99.
  
   
 0.648
EDS73959.1
Cell envelope-like function transcriptional attenuator common domain protein; COG: COG1316 Transcriptional regulator; Psort location: CytoplasmicMembrane, score: 9.99.
  
   
 0.642
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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