Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS74396.1Putative membrane protein; COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: CytoplasmicMembrane, score: 9.99. (303 aa)    
Predicted Functional Partners:
EDS74397.1
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: oih:OB1842 4.5e-42 dacF; D-alanyl-D-alanine carboxypeptidase K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
       0.773
EDS74398.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.570
EDS74395.1
F5/8 type C domain protein; KEGG: cpe:CPE1364 1.2e-207 beta-N-acetylhexosaminidase K01207; COG: COG3525 N-acetyl-beta-hexosaminidase; Psort location: Extracellular, score: 9.73.
 
     0.516
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.494
EDS75982.1
Hypothetical protein; KEGG: bce:BC2348 0.00018 acetyltransferase K00680; COG: COG1357 Uncharacterized low-complexity proteins; Psort location: Cytoplasmic, score: 8.87.
   
   0.437
EDS74761.1
Hypothetical protein; COG: NOG12915 non supervised orthologous group.
   
   0.427
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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