STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74401.1Oxidoreductase, aldo/keto reductase family protein; KEGG: cgl:NCgl1003 6.8e-78 cgl1048; aldo/keto reductase K03378; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase; Psort location: Cytoplasmic, score: 8.87. (291 aa)    
Predicted Functional Partners:
EDS74404.1
Flavodoxin family protein; KEGG: bcz:BCZK1264 0.00044 fldA; flavodoxin K00536; COG: COG0716 Flavodoxins.
      0.923
EDS74629.1
Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.905
EDS75207.1
Flavodoxin; COG: COG0716 Flavodoxins.
      0.903
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.851
EDS74402.1
Flavin reductase; KEGG: btk:BT9727_4666 6.8e-06 NAD(P)H dehydrogenase (quinone) K00355; COG: COG0655 Multimeric flavodoxin WrbA.
  
    0.775
EDS75105.1
KEGG: ctc:CTC01806 2.7e-209 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
   
 0.764
EDS74400.1
Hypothetical protein; COG: COG4925 Uncharacterized conserved protein.
       0.741
EDS74041.1
KEGG: ypk:y1125 5.9e-24 hypothetical protein K00100; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase.
  
     0.718
EDS74403.1
Hypothetical protein; COG: COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain; Psort location: Cytoplasmic, score: 8.87.
       0.679
EDS74241.1
Oxidoreductase, aldo/keto reductase family protein; KEGG: lpl:lp_2890 2.5e-87 oxidoreductase; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score: 8.87.
 
0.627
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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