STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74410.1Glyoxalase family protein; KEGG: bth:BT1580 1.0e-42 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: Cytoplasmic, score: 8.87. (122 aa)    
Predicted Functional Partners:
EDS75001.1
Metallo-beta-lactamase domain protein; KEGG: fnu:FN1162 2.7e-26 hydroxyacylglutathione hydrolase K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases.
 
 0.939
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.883
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
 0.826
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.813
EDS75473.1
KEGG: bth:BT4678 3.0e-100 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87.
    
  0.801
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
EDS74409.1
KEGG: cac:CAC0566 1.3e-97 malate dehydrogenase K00025; COG: COG2055 Malate/L-lactate dehydrogenases; Psort location: Cytoplasmic, score: 8.87; Belongs to the LDH2/MDH2 oxidoreductase family.
       0.752
EDS74419.1
Hypothetical protein; KEGG: fnu:FN1387 8.1e-27 metal dependent hydrolase; COG: COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.
 
    0.740
EDS74936.1
Hypothetical protein; KEGG: fnu:FN1041 2.0e-14 acetyltransferase K00680; COG: COG4866 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.656
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.620
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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