STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74410.1Glyoxalase family protein; KEGG: bth:BT1580 1.0e-42 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: Cytoplasmic, score: 8.87. (122 aa)    
Predicted Functional Partners:
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.979
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 0.873
EDS74588.1
DHHA2 domain protein; KEGG: cpe:CPE2055 1.0e-152 probable manganase-dependent inorganic pyrophosphatase K01507; COG: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.861
EDS75001.1
Metallo-beta-lactamase domain protein; KEGG: fnu:FN1162 2.7e-26 hydroxyacylglutathione hydrolase K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases.
 
  
 0.848
EDS75817.1
Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
    
  0.835
EDS74574.1
FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87.
  
 
 0.769
EDS74409.1
KEGG: cac:CAC0566 1.3e-97 malate dehydrogenase K00025; COG: COG2055 Malate/L-lactate dehydrogenases; Psort location: Cytoplasmic, score: 8.87; Belongs to the LDH2/MDH2 oxidoreductase family.
       0.752
EDS74419.1
Hypothetical protein; KEGG: fnu:FN1387 8.1e-27 metal dependent hydrolase; COG: COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.
 
    0.731
accA
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
  
 
 0.726
EDS74965.1
Rubredoxin; KEGG: syn:sll0550 3.3e-46 flavoprotein; COG: COG0426 Uncharacterized flavoproteins; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.706
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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