STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74418.1acyl-CoA thioester hydrolase, YbgC/YbaW family; KEGG: bcz:BCZK3313 3.2e-23 possible 4-hydroxybenzoyl-CoA thioesterase K01075; COG: COG0824 Predicted thioesterase; Psort location: Cytoplasmic, score: 8.87. (137 aa)    
Predicted Functional Partners:
fabD
[acyl-carrier-protein] S-malonyltransferase; KEGG: cno:NT01CX_0924 1.8e-70 fabD; malonyl CoA-acyl carrier protein transacylase K00645; COG: COG0331 (acyl-carrier-protein) S-malonyltransferase; Psort location: Cytoplasmic, score: 8.87.
  
 0.885
EDS74419.1
Hypothetical protein; KEGG: fnu:FN1387 8.1e-27 metal dependent hydrolase; COG: COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.
   
   0.798
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.784
EDS74420.1
DNA-binding regulatory protein, YebC/PmpR family; KEGG: eci:UTI89_C2068 3.8e-36 yebC; hypothetical protein K00975; COG: COG0217 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.711
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
    
 0.701
fabHA
Beta-ketoacyl-acyl-carrier-protein synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 0.696
fabF
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
    
 0.686
EDS75259.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: rso:RSc0215 1.7e-33 RS00647; short chain dehydrogenase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 0.635
EDS74637.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: stm:STM2445 2.8e-81 ucpA; putative oxidoreductase; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98.
  
 0.635
EDS74745.1
KEGG: cpe:CPE1070 7.8e-45 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98.
  
 0.635
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: medium (68%) [HD]