Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDS74425.1TrkA N-terminal domain protein; KEGG: cjr:CJE0889 0.0039 ddl; D-alanylalanine synthetase K01921; COG: COG0569 K+ transport systems, NAD-binding component; Psort location: Cytoplasmic, score: 10.00. (221 aa)    
Predicted Functional Partners:
EDS74424.1
KEGG: shn:Shewana3_0031 7.8e-05 potassium uptake protein, TrkH family K00961; COG: COG0168 Trk-type K+ transport systems, membrane components; Psort location: CytoplasmicMembrane, score: 10.00.
 
 0.992
EDS74422.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: gox:GOX1630 5.9e-63 putative oxidoreductase K00100; COG: COG2509 Uncharacterized FAD-dependent dehydrogenases.
  
    0.596
EDS74421.1
Flavoprotein family protein; KEGG: gox:GOX1717 0.00024 putative oxidoreductase K00100; COG: COG2081 Predicted flavoproteins; Psort location: Cytoplasmic, score: 8.87.
       0.594
mntP
Hypothetical protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.
       0.594
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.570
sun
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.521
EDS74426.1
COG: COG3870 Uncharacterized protein conserved in bacteria.
     
 0.510
EDS74420.1
DNA-binding regulatory protein, YebC/PmpR family; KEGG: eci:UTI89_C2068 3.8e-36 yebC; hypothetical protein K00975; COG: COG0217 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.421
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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