STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS74493.1Diacylglycerol kinase catalytic domain protein; KEGG: eci:UTI89_C2362 1.2e-09 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; Psort location: Cytoplasmic, score: 8.87. (286 aa)    
Predicted Functional Partners:
EDS75543.1
Lipid kinase, YegS/Rv2252/BmrU family; KEGG: eci:UTI89_C2362 2.6e-17 hypothetical protein; COG: COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.
  
 
  0.920
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 0.838
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
  
 
 0.820
cdsA
KEGG: bca:BCE_3863 1.8e-38 cdsA; phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.795
EDS74209.1
Acyltransferase; KEGG: ctc:CTC00551 1.7e-26 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655; COG: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Psort location: Cytoplasmic, score: 8.87.
    
 0.790
EDS73937.1
Glycosyltransferase, group 1 family protein; KEGG: pub:SAR11_0559 7.0e-15 rfaK; 1,2-N-acetylglucosaminetransferase; COG: COG0438 Glycosyltransferase; Psort location: CytoplasmicMembrane, score: 9.75.
  
 
 0.641
EDS75268.1
KEGG: oih:OB1952 2.4e-20 dgkA; diacylglycerol kinase K00901; COG: COG0818 Diacylglycerol kinase.
     
 0.631
gpsA
KEGG: bce:BC1505 5.7e-74 gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase K00057; COG: COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.591
EDS74492.1
Hypothetical protein; KEGG: ser:SERP0888 0.00013 sensor histidine kinase, putative K02480; Psort location: CytoplasmicMembrane, score: 9.99.
       0.549
EDS73746.1
Phospholipase D domain protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
  
 
 0.481
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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