Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trpStryptophan--tRNA ligase; KEGG: bfs:BF3809 2.6e-133 trpS; tryptophanyl-tRNA synthetase K01867; COG: COG0180 Tryptophanyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family. (357 aa)    
Predicted Functional Partners:
EDS74839.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.702
pheT
KEGG: gka:GK2706 2.5e-151 phenylalanyl-tRNA synthetase beta subunit K01890; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.698
serS
serine--tRNA ligase; KEGG: mhu:Mhun_2507 1.1e-86 seryl-tRNA synthetase K01875; COG: COG0172 Seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00.
  
 
 0.644
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.620
leuS
leucine--tRNA ligase; KEGG: gka:GK2842 0. leuS; leucyl-tRNA synthetase K01869; COG: COG0495 Leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.613
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.602
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
    
 
 0.595
EDS73688.1
COG: COG3192 Ethanolamine utilization protein; Psort location: CytoplasmicMembrane, score: 9.99.
       0.594
EDS74218.1
Chorismate mutase; KEGG: aae:aq_951 3.3e-53 pheA; chorismate mutase/prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.591
EDS73687.1
Hypothetical protein; KEGG: mmy:MSC_0769 0.0030 pcrA; ATP-dependent DNA helicase K03657; COG: COG3210 Large exoproteins involved in heme utilization or adhesion; Psort location: Cytoplasmic, score: 8.87.
       0.590
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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