STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73730.1Acetyltransferase, GNAT family; KEGG: lsl:LSL_1673 2.1e-21 wecD; acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87. (164 aa)    
Predicted Functional Partners:
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.704
EDS75721.1
Acetyltransferase, GNAT family; KEGG: lsl:LSL_1673 4.3e-12 wecD; acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87.
  
     0.699
EDS73731.1
Hypothetical protein; KEGG: mta:Moth_1016 0.0043 catalase K00429; COG: COG1633 Uncharacterized conserved protein.
       0.559
EDS73729.1
HD domain protein; COG: NOG14059 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.531
EDS74353.1
Hypothetical protein; KEGG: sha:SH0994 0.0026 agrC; AgrC K07706; COG: NOG17531 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.458
EDS74243.1
Bacterial transferase hexapeptide repeat protein; KEGG: spy:SPy1065 5.8e-65 putative acetyltransferase K00680; COG: COG0110 Acetyltransferase (isoleucine patch superfamily); Psort location: Cytoplasmic, score: 9.65.
    
 0.444
EDS74549.1
Beta-eliminating lyase; KEGG: cac:CAC3420 7.4e-88 low specificity L-threonine aldolase K01620; COG: COG2008 Threonine aldolase.
 
 
  0.427
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (34%) [HD]