STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73770.1Phosphodiesterase family protein; KEGG: eci:UTI89_C2584 3.5e-42 yfcE; hypothetical protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87. (183 aa)    
Predicted Functional Partners:
EDS73771.1
Hypothetical protein; COG: COG4832 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.775
EDS73772.1
KEGG: tbr:Tb927.7.5790 0.0013 protein disulfide isomerase K01829; Psort location: Cytoplasmic, score: 8.87.
 
    0.613
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.592
rlmH
rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
  
    0.525
EDS73776.1
Metallo-beta-lactamase domain protein; KEGG: fnu:FN0900 1.9e-25 metal dependent hydrolase; COG: COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.
     
 0.520
EDS73773.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.517
EDS73774.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.26.
       0.517
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.513
EDS74843.1
Hypothetical protein; KEGG: ctc:CTC01982 0.0016 L-serine dehydratase alpha subunit K01752; COG: COG3681 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 9.98; Belongs to the UPF0597 family.
  
     0.467
glnA-2
Glutamate--ammonia ligase, catalytic domain protein; KEGG: tte:TTE0821 1.3e-200 glnA; Glutamine synthase K01915; COG: COG3968 Uncharacterized protein related to glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
       0.454
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.