STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmHrRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (159 aa)    
Predicted Functional Partners:
EDS73776.1
Metallo-beta-lactamase domain protein; KEGG: fnu:FN0900 1.9e-25 metal dependent hydrolase; COG: COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.
       0.820
EDS73773.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
       0.764
EDS73772.1
KEGG: tbr:Tb927.7.5790 0.0013 protein disulfide isomerase K01829; Psort location: Cytoplasmic, score: 8.87.
       0.762
EDS73774.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.26.
       0.762
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.761
EDS74138.1
RNA methyltransferase, RsmD family; KEGG: lsl:LSL_0660 1.2e-34 methyltransferase K00599; COG: COG0742 N6-adenine-specific methylase.
 
   
 0.545
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.536
EDS73770.1
Phosphodiesterase family protein; KEGG: eci:UTI89_C2584 3.5e-42 yfcE; hypothetical protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87.
  
    0.525
rpmE
Ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
       0.522
EDS73771.1
Hypothetical protein; COG: COG4832 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.510
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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