Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDS73807.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spj:MGAS2096_Spy1107 3.3e-46 two-component system histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49. (306 aa)    
Predicted Functional Partners:
EDS73808.1
Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 2.2e-26 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.962
EDS73805.1
Efflux ABC transporter, permease protein; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
 
   
 0.903
EDS75120.1
Response regulator receiver domain protein; KEGG: eci:UTI89_C0420 1.9e-41 phoB; positive response regulator for pho regulon K07657; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
   0.836
EDS74715.1
KEGG: rha:RHA1_ro05622 3.6e-33 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.835
EDS75916.1
Response regulator receiver domain protein; KEGG: fal:FRAAL1628 2.5e-39 response regulator in two-component regulatory system; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.832
EDS76001.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 6.2e-36 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.829
EDS75693.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 1.4e-36 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.817
EDS75435.1
Response regulator receiver domain protein; KEGG: ava:Ava_1878 9.6e-40 two component transcriptional regulator, winged helix family K07659; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.815
EDS74584.1
KEGG: rha:RHA1_ro05622 2.7e-42 response regulator (protein-glutamate methylesterase) K07669; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
   0.812
EDS73806.1
ABC transporter, ATP-binding protein; KEGG: fal:FRAAL2864 7.8e-45 putative transport protein of outer membrane lipoproteins (ABC superfamily, atp_bind) (partial match); COG: COG1136 ABC-type antimicrobial peptide transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.788
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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