STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73831.1CDP-alcohol phosphatidyltransferase; KEGG: cac:CAC0798 1.2e-27 phosphatidylserine synthase K00998; COG: COG1183 Phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00. (185 aa)    
Predicted Functional Partners:
psd
KEGG: cac:CAC0799 4.1e-71 psd; phosphatidylserine decarboxylase K01613; COG: COG0688 Phosphatidylserine decarboxylase; Belongs to the phosphatidylserine decarboxylase family.
 
 
 0.997
EDS75594.1
Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: cac:CAC3596 2.8e-24 pgsA; phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.928
cdsA
KEGG: bca:BCE_3863 1.8e-38 cdsA; phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.919
pgsA
KEGG: lwe:lwe1412 3.2e-39 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.915
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.901
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.900
EDS75473.1
KEGG: bth:BT4678 3.0e-100 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87.
     
  0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.900
cysE
KEGG: gka:GK0084 1.5e-50 serine O-acetyltransferase K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score: 9.98.
    
  0.802
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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