STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73849.1Hydrolase, TatD family; KEGG: bca:BCE_0037 1.9e-66 deoxyribonuclease, TatD family K03424; COG: COG0084 Mg-dependent DNase; Psort location: Cytoplasmic, score: 8.87. (252 aa)    
Predicted Functional Partners:
EDS76064.1
Radical SAM domain protein; KEGG: pca:Pcar_1695 3.7e-31 deoxyribonuclease, TatD family K03424; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87.
     0.935
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 0.875
EDS73848.1
3D domain protein; COG: COG3584 Uncharacterized protein conserved in bacteria.
       0.774
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.651
fabD
[acyl-carrier-protein] S-malonyltransferase; KEGG: cno:NT01CX_0924 1.8e-70 fabD; malonyl CoA-acyl carrier protein transacylase K00645; COG: COG0331 (acyl-carrier-protein) S-malonyltransferase; Psort location: Cytoplasmic, score: 8.87.
      0.632
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
 
    0.602
EDS73854.1
KEGG: sha:SH2518 7.6e-47 ksgA; putative dimethyladenosine transferase K02528; COG: COG0030 Dimethyladenosine transferase (rRNA methylation); Psort location: Cytoplasmic, score: 8.87.
 
  
 0.579
rnmV
Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
  
  
 0.488
EDS73847.1
Hypothetical protein; KEGG: cpv:cgd7_440 0.00019 RIO-like kinase domain; N-terminal region conserved K07179; COG: KOG1181 FOG: Low-complexity; Psort location: Cytoplasmic, score: 8.87.
       0.485
glmU
UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
       0.484
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.