STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73861.1Glycine radical domain protein; KEGG: cno:NT01CX_0385 1.3e-67 pyruvate formate-lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98. (756 aa)    
Predicted Functional Partners:
EDS73862.1
Glycyl-radical enzyme activating protein family protein; KEGG: ctc:CTC00937 5.8e-65 pyruvate formate-lyase K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.65.
  
 0.969
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
    
 0.927
EDS74629.1
Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.874
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
   
 
 0.866
EDS75438.1
Glycyl-radical enzyme activating protein family protein; KEGG: tko:TK0290 3.5e-58 pyruvate-formate lyase-activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98.
  
 0.864
EDS75200.1
Glycyl-radical enzyme activating protein family protein; KEGG: cno:NT01CX_1221 2.6e-62 pflC; glycerol dehydratase activator K00538; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98.
  
 0.863
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.844
EDS74445.1
4Fe-4S binding domain protein; KEGG: tte:TTE0893 7.2e-225 nuoF; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98.
     
 0.828
EDS74444.1
Hydrogenase, Fe-only; KEGG: tte:TTE0894 1.4e-180 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
     
 0.805
EDS73863.1
Transcriptional regulator, DeoR family; COG: COG1349 Transcriptional regulators of sugar metabolism.
  
 
 0.779
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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