STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (271 aa)    
Predicted Functional Partners:
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
  
  
 0.922
EDS75491.1
Hypothetical protein; KEGG: sha:SH0521 2.0e-10 ptsG; phosphotransferase system enzyme II K02777:K02778:K02779; COG: COG2190 Phosphotransferase system IIA components.
 
 
  0.910
EDS73779.1
KEGG: sar:SAR0235 1.9e-137 putative PTS transport system, IIBC component K02790:K02791; COG: COG1264 Phosphotransferase system IIB components; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
  0.895
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
  
 0.877
EDS74588.1
DHHA2 domain protein; KEGG: cpe:CPE2055 1.0e-152 probable manganase-dependent inorganic pyrophosphatase K01507; COG: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; Psort location: Cytoplasmic, score: 8.87.
    
  0.866
EDS74810.1
Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
 
 
  0.856
EDS75113.1
Molybdopterin binding domain protein; KEGG: mmu:319945 0.00014 Flad1; RFad1, flavin adenine dinucleotide synthetase, homolog (yeast) K00953; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.837
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
   
 
  0.834
EDS74818.1
KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87.
  
 
  0.824
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.820
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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