STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73874.1COG: COG2832 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.99. (126 aa)    
Predicted Functional Partners:
EDS73877.1
ABC transporter, ATP-binding protein; KEGG: cch:Cag_0716 1.1e-70 ATPase K06148; COG: COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
  0.968
EDS73875.1
Hypothetical protein; COG: NOG16835 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.950
EDS73876.1
ABC transporter, ATP-binding protein; KEGG: bur:Bcep18194_B1962 1.2e-64 ABC efflux pump, fused ATPase and inner membrane subunits K06021:K06022; COG: COG1132 ABC-type multidrug transport system, ATPase and permease components; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.946
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.517
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.517
EDS73872.1
tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: tdn:Tmden_0005 4.2e-46 polynucleotide adenylyltransferase region K00974; COG: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Psort location: Cytoplasmic, score: 8.87.
       0.517
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.517
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
       0.507
EDS75672.1
KEGG: bca:BCE_4668 1.8e-61 iron compound ABC transporter, ATP-binding protein K02013; COG: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; Psort location: CytoplasmicMembrane, score: 9.82.
    0.489
EDS73878.1
Polysaccharide deacetylase; KEGG: spd:SPD_1309 1.4e-36 pgdA; peptidoglycan GlcNAc deacetylase K01463; COG: COG0726 Predicted xylanase/chitin deacetylase.
       0.412
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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