STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (321 aa)    
Predicted Functional Partners:
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 0.994
pyk-2
Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
  
 0.986
EDS75030.1
KEGG: cno:NT01CX_0234 4.8e-116 citrate synthase I K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98.
  
 0.984
pyk
Pyruvate kinase; KEGG: oih:OB2171 3.5e-129 pykA; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
  
 0.980
EDS73752.1
KEGG: cno:NT01CX_0140 1.6e-202 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 8.87.
  
 0.954
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
  
 0.947
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.929
ilvB
KEGG: chy:CHY_0517 2.1e-163 ilvB1; acetolactate synthase, large subunit, biosynthetic type K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87.
  
 0.923
pgi
KEGG: bli:BL02591 3.9e-137 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
  
 0.921
pflB
KEGG: bli:BL01863 5.4e-275 hypothetical formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.912
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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