Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDS73884.1LPXTG-motif cell wall anchor domain protein; KEGG: tte:TTE0006 1.3e-34 Alpha-glucosidases, family 31 of glycosyl hydrolases K01187; COG: COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Psort location: Extracellular, score: 9.75. (2169 aa)    
Predicted Functional Partners:
nagJ
O-GlcNAcase NagJ; KEGG: cpe:CPE0191 4.1e-65 nagH; hyaluronoglucosaminidase K01197; COG: NOG11197 non supervised orthologous group; Psort location: Cellwall, score: 9.49.
 
 
   0.632
EDS75992.1
Hypothetical protein; KEGG: fnu:FN1984 0.00068 thioredoxin reductase / glutaredoxin-like protein K00384; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 8.87.
  
 0.622
EDS75974.1
Hypothetical protein; KEGG: cpe:CPE1876 2.3e-61 alpha-L-fucosidase K01206; COG: COG3669 Alpha-L-fucosidase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.537
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.498
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
   0.497
EDS74568.1
DnaJ domain protein; COG: COG2214 DnaJ-class molecular chaperone; Psort location: Cytoplasmic, score: 9.65.
   
   0.497
EDS73883.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
       0.496
EDS74691.1
BNR/Asp-box repeat protein; KEGG: rba:RB3353 4.6e-10 sialidase [precursor] K01186; COG: NOG23393 non supervised orthologous group; Psort location: Extracellular, score: 9.98.
 
    0.493
EDS73752.1
KEGG: cno:NT01CX_0140 1.6e-202 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 8.87.
    
   0.483
EDS75091.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.469
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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