STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73884.1LPXTG-motif cell wall anchor domain protein; KEGG: tte:TTE0006 1.3e-34 Alpha-glucosidases, family 31 of glycosyl hydrolases K01187; COG: COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Psort location: Extracellular, score: 9.75. (2169 aa)    
Predicted Functional Partners:
EDS75824.1
LPXTG-motif cell wall anchor domain protein; KEGG: smu:SMU.78 7.2e-234 fruA; fructan hydrolase; exo-beta-D-fructosidase; fructanase, FruA K03332; COG: COG1621 Beta-fructosidases (levanase/invertase); Psort location: Cellwall, score: 9.93.
   
 
0.841
nagJ
O-GlcNAcase NagJ; KEGG: cpe:CPE0191 4.1e-65 nagH; hyaluronoglucosaminidase K01197; COG: NOG11197 non supervised orthologous group; Psort location: Cellwall, score: 9.49.
 
 
 0.684
EDS75974.1
Hypothetical protein; KEGG: cpe:CPE1876 2.3e-61 alpha-L-fucosidase K01206; COG: COG3669 Alpha-L-fucosidase; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.596
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.591
EDS74568.1
DnaJ domain protein; COG: COG2214 DnaJ-class molecular chaperone; Psort location: Cytoplasmic, score: 9.65.
   
 
 0.591
EDS73701.1
F5/8 type C domain protein; KEGG: cpe:CPE1364 2.6e-08 beta-N-acetylhexosaminidase K01207; COG: NOG08372 non supervised orthologous group.
 
  
  0.584
EDS73752.1
KEGG: cno:NT01CX_0140 1.6e-202 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 8.87.
    
   0.562
EDS74691.1
BNR/Asp-box repeat protein; KEGG: rba:RB3353 4.6e-10 sialidase [precursor] K01186; COG: NOG23393 non supervised orthologous group; Psort location: Extracellular, score: 9.98.
 
  
  0.557
EDS75992.1
Hypothetical protein; KEGG: fnu:FN1984 0.00068 thioredoxin reductase / glutaredoxin-like protein K00384; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.538
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
   0.531
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (26%) [HD]