STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family. (283 aa)    
Predicted Functional Partners:
speD
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
 
 
 0.998
EDS73899.1
Orn/Lys/Arg decarboxylase, major domain protein; KEGG: spn:SP_0916 4.2e-181 lysine decarboxylase K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases; Psort location: Cytoplasmic, score: 8.87.
 
 0.996
speB
Agmatinase; KEGG: cpe:CPE0551 6.9e-101 speB; probable agmatinase K01480; COG: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Psort location: Cytoplasmic, score: 8.87; Belongs to the arginase family.
 
 
 0.992
EDS75509.1
Conserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.901
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.900
mtnN-2
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.900
nspC
KEGG: hpa:HPAG1_0020 2.5e-87 carboxynorspermidine decarboxylase K01618; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.850
LYS1
KEGG: spd:SPD_0812 4.2e-165 lys1; saccharopine dehydrogenase K00290; COG: COG1748 Saccharopine dehydrogenase and related proteins; Psort location: Cytoplasmic, score: 8.87.
       0.799
EDS75223.1
ABC transporter, permease protein; KEGG: cdi:DIP0495 2.8e-09 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; COG: COG0687 Spermidine/putrescine-binding periplasmic protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.608
EDS73894.1
Hypothetical protein.
       0.581
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.