STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speDS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (261 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
 
 
 0.998
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.940
nspC
KEGG: hpa:HPAG1_0020 2.5e-87 carboxynorspermidine decarboxylase K01618; COG: COG0019 Diaminopimelate decarboxylase; Psort location: Cytoplasmic, score: 8.87.
     
 0.819
speB
Agmatinase; KEGG: cpe:CPE0551 6.9e-101 speB; probable agmatinase K01480; COG: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Psort location: Cytoplasmic, score: 8.87; Belongs to the arginase family.
     
 0.819
EDS73899.1
Orn/Lys/Arg decarboxylase, major domain protein; KEGG: spn:SP_0916 4.2e-181 lysine decarboxylase K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases; Psort location: Cytoplasmic, score: 8.87.
     
 0.801
LYS1
KEGG: spd:SPD_0812 4.2e-165 lys1; saccharopine dehydrogenase K00290; COG: COG1748 Saccharopine dehydrogenase and related proteins; Psort location: Cytoplasmic, score: 8.87.
       0.799
EDS75223.1
ABC transporter, permease protein; KEGG: cdi:DIP0495 2.8e-09 putative molybdenum ABC transport system (integral membrane and ATP-binding proteins) K02017:K02018; COG: COG0687 Spermidine/putrescine-binding periplasmic protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.609
EDS73894.1
Hypothetical protein.
       0.581
EDS75105.1
KEGG: ctc:CTC01806 2.7e-209 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87.
     
 0.441
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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