STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73921.1Oxidoreductase, aldo/keto reductase family protein; KEGG: bce:BC0217 9.4e-33 2,5-diketo-D-gluconic acid reductase K00100; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase; Psort location: Cytoplasmic, score: 8.87. (150 aa)    
Predicted Functional Partners:
EDS73922.1
Oxidoreductase, aldo/keto reductase family protein; KEGG: sab:SAB0652 3.6e-24 probable oxidoreductase K00120; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase.
     0.994
EDS74041.1
KEGG: ypk:y1125 5.9e-24 hypothetical protein K00100; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase.
 
0.598
EDS74401.1
Oxidoreductase, aldo/keto reductase family protein; KEGG: cgl:NCgl1003 6.8e-78 cgl1048; aldo/keto reductase K03378; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase; Psort location: Cytoplasmic, score: 8.87.
 
0.597
EDS75519.1
Protein phosphatase 2C; KEGG: bsu:BG13390 1.1e-43 prpC, yloO; PP2C protein phosphatase K01090; COG: COG0631 Serine/threonine protein phosphatase; Psort location: Cytoplasmic, score: 8.87.
    
   0.543
EDS76066.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.525
EDS73773.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.525
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.507
EDS74568.1
DnaJ domain protein; COG: COG2214 DnaJ-class molecular chaperone; Psort location: Cytoplasmic, score: 9.65.
    
 
 0.507
EDS73923.1
Arylsulfatase; KEGG: eba:ebA3535 2.1e-44 mdoB; phosphoglycerol transferase I K01002; COG: COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Psort location: CytoplasmicMembrane, score: 9.75.
       0.490
EDS74629.1
Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.464
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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