STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rfbBKEGG: ljo:LJ1049 1.8e-132 dTDP-D-glucose 4,6-dehydratase K01710; COG: COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (341 aa)    
Predicted Functional Partners:
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 
 0.999
rfbA-2
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 0.999
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
 0.973
cps4K
Capsular polysaccharide biosynthesis protein Cps4K; KEGG: vfi:VF0192 2.6e-60 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.962
EDS75171.1
Hypothetical protein; KEGG: vfi:VF0192 0.00030 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases.
  
 
 0.962
EDS75176.1
NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 4.6e-72 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.962
EDS74358.1
NAD dependent epimerase/dehydratase family protein; KEGG: vfi:VF0192 6.5e-73 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases.
  
 
 0.962
EDS75394.1
DegT/DnrJ/EryC1/StrS aminotransferase family protein; KEGG: cno:NT01CX_1463 6.9e-101 spsC; spore coat polysaccharide biosynthesis protein SpsC K01726; COG: COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87; Belongs to the DegT/DnrJ/EryC1 family.
 
 
 0.953
EDS75375.1
Nucleotide sugar dehydrogenase; KEGG: tdn:Tmden_1968 1.4e-150 UDP-glucose 6-dehydrogenase K00012; COG: COG1004 Predicted UDP-glucose 6-dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.919
EDS73937.1
Glycosyltransferase, group 1 family protein; KEGG: pub:SAR11_0559 7.0e-15 rfaK; 1,2-N-acetylglucosaminetransferase; COG: COG0438 Glycosyltransferase; Psort location: CytoplasmicMembrane, score: 9.75.
  
 
 0.872
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.