Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rfbA-2Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)    
Predicted Functional Partners:
rfbB
KEGG: ljo:LJ1049 1.8e-132 dTDP-D-glucose 4,6-dehydratase K01710; COG: COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 0.999
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
 0.997
rfbD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
 0.994
EDS75375.1
Nucleotide sugar dehydrogenase; KEGG: tdn:Tmden_1968 1.4e-150 UDP-glucose 6-dehydrogenase K00012; COG: COG1004 Predicted UDP-glucose 6-dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.989
galU
KEGG: ctc:CTC02269 4.2e-94 UTP-glucose-1-phosphate uridylyltransferase K00963; COG: COG1210 UDP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score: 8.87.
 
 
0.956
EDS75272.1
Polysaccharide biosynthesis protein; COG: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.939
EDS76122.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: gka:GK3297 1.2e-151 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.917
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 
0.900
glgD
KEGG: cpr:CPR_0087 2.1e-67 glgD; glucose-1-phosphate adenylyltransferase, GlgD subunit K00975; COG: COG0448 ADP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score: 8.87.
    
  0.900
cps4K
Capsular polysaccharide biosynthesis protein Cps4K; KEGG: vfi:VF0192 2.6e-60 UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase K00100; COG: COG0451 Nucleoside-diphosphate-sugar epimerases; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.876
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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