STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73960.1Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (271 aa)    
Predicted Functional Partners:
EDS74947.1
Putative SpoIVB peptidase; KEGG: btl:BALH_3781 6.9e-53 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.
     0.920
spoIIAB
Anti-sigma F factor; KEGG: cpr:CPR_2021 9.4e-33 spoIIAB; anti-sigma F factor K06379; COG: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); Psort location: Cytoplasmic, score: 8.87.
 
  
 0.804
EDS73819.1
KEGG: oih:OB0074 1.3e-40 stage II sporulation protein E K06382; COG: COG2208 Serine phosphatase RsbU, regulator of sigma subunit; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.802
spoIVA
Stage IV sporulation protein A; KEGG: cno:NT01CX_0264 0.0018 hemA; glutamyl-tRNA reductase K00155; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.799
spoIIP
Stage II sporulation protein P; COG: NOG06343 non supervised orthologous group.
  
   
 0.796
EDS74922.1
RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.795
spoVAD
Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group.
  
   
 0.794
gpr
KEGG: bli:BL02089 5.7e-42 gpr; spore protease K06012; COG: NOG08575 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
   
 0.788
sigE
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.788
sigF
KEGG: hpa:HPAG1_0089 4.4e-23 RNA polymerase sigma-80 factor K00960; COG: COG1191 DNA-directed RNA polymerase specialized sigma subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the sigma-70 factor family.
  
  
 0.786
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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