STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS73978.1Acetyltransferase, GNAT family; KEGG: lla:L170990 1.2e-41 yfhA; putative acetyltransferase K03827; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87. (147 aa)    
Predicted Functional Partners:
EDS75404.1
KEGG: ssp:SSP0322 1.7e-40 putative 6-O-methylguanine DNA methyltransferase K00567; COG: COG0350 Methylated DNA-protein cysteine methyltransferase; Psort location: Cytoplasmic, score: 8.87.
      0.899
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
    0.761
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
  0.704
EDS73977.1
KEGG: bpm:BURPS1710b_A2293 0.00072 TetR-family regulatory protein K00356; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
     
 0.611
EDS75322.1
Hypothetical protein; KEGG: rba:RB763 6.7e-09 iduronate-2-sulfatase K01136; COG: NOG08576 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.518
EDS75112.1
Acetyltransferase, GNAT family; KEGG: fnu:FN1294 4.8e-13 ribosomal-protein-alanine acetyltransferase K00676; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
 
 
 0.502
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.