STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (112 aa)    
Predicted Functional Partners:
EDS73990.1
Membrane protein insertase, YidC/Oxa1 family; COG: COG0706 Preprotein translocase subunit YidC; Psort location: CytoplasmicMembrane, score: 9.99.
  
  
 0.979
rpmH
COG: COG0230 Ribosomal protein L34; Psort location: Extracellular, score: 8.82; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.972
EDS73991.1
R3H domain protein; COG: COG1847 Predicted RNA-binding protein; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.885
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
  
 0.864
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
   
  
 0.833
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
  
 0.827
rpmB
COG: COG0227 Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.825
rex
CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
   
    0.823
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
    0.819
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
    0.815
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (22%) [HD]