| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS73995.1 | EDS73997.1 | CLOSPI_02421 | CLOSPI_02423 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: lsa:LSA1519 0.0010 putative teichoic acid/polysaccharide glycosyl transferase, family 2 K00754; Psort location: CytoplasmicMembrane, score: 9.75. | 0.505 |
| EDS73995.1 | EDS74056.1 | CLOSPI_02421 | CLOSPI_02482 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | Glycosyl hydrolase family 2, sugar binding domain protein; KEGG: cpf:CPF_1474 0. lacZ; beta-galactosidase K01190; COG: COG3250 Beta-galactosidase/beta-glucuronidase; Psort location: Extracellular, score: 8.07; Belongs to the glycosyl hydrolase 2 family. | 0.535 |
| EDS73995.1 | EDS74629.1 | CLOSPI_02421 | CLOSPI_01684 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.577 |
| EDS73995.1 | EDS74705.1 | CLOSPI_02421 | CLOSPI_01482 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | Hypothetical protein; KEGG: hit:NTHI1634 2.3e-14 NAD-dependent deacetylase sirtuin 5 K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.533 |
| EDS73995.1 | EDS75394.1 | CLOSPI_02421 | CLOSPI_00788 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | DegT/DnrJ/EryC1/StrS aminotransferase family protein; KEGG: cno:NT01CX_1463 6.9e-101 spsC; spore coat polysaccharide biosynthesis protein SpsC K01726; COG: COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87; Belongs to the DegT/DnrJ/EryC1 family. | 0.787 |
| EDS73995.1 | EDS75723.1 | CLOSPI_02421 | CLOSPI_00233 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | Aldehyde dehydrogenase (NAD) family protein; KEGG: ctc:CTC02523 8.9e-108 ywdH; putative aldehyde dehydrogenase YwdH K00128; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.704 |
| EDS73995.1 | EDS75995.1 | CLOSPI_02421 | CLOSPI_00108 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | Transcriptional regulator, Sir2 family; KEGG: tte:TTE1570 7.9e-13 sir2; NAD-dependent protein deacetylase, Sir2 family K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family; Psort location: Cytoplasmic, score: 8.87. | 0.533 |
| EDS73995.1 | lysS | CLOSPI_02421 | CLOSPI_02465 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | lysine--tRNA ligase; KEGG: gka:GK0074 3.2e-167 lysyl-tRNA synthetase (lysine--tRNA ligase) K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.583 |
| EDS73995.1 | rfbB | CLOSPI_02421 | CLOSPI_02378 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | KEGG: ljo:LJ1049 1.8e-132 dTDP-D-glucose 4,6-dehydratase K01710; COG: COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.558 |
| EDS73995.1 | trmE | CLOSPI_02421 | CLOSPI_02422 | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.512 |
| EDS73997.1 | EDS73995.1 | CLOSPI_02423 | CLOSPI_02421 | Hypothetical protein; KEGG: lsa:LSA1519 0.0010 putative teichoic acid/polysaccharide glycosyl transferase, family 2 K00754; Psort location: CytoplasmicMembrane, score: 9.75. | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | 0.505 |
| EDS73997.1 | trmE | CLOSPI_02423 | CLOSPI_02422 | Hypothetical protein; KEGG: lsa:LSA1519 0.0010 putative teichoic acid/polysaccharide glycosyl transferase, family 2 K00754; Psort location: CytoplasmicMembrane, score: 9.75. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.773 |
| EDS74056.1 | EDS73995.1 | CLOSPI_02482 | CLOSPI_02421 | Glycosyl hydrolase family 2, sugar binding domain protein; KEGG: cpf:CPF_1474 0. lacZ; beta-galactosidase K01190; COG: COG3250 Beta-galactosidase/beta-glucuronidase; Psort location: Extracellular, score: 8.07; Belongs to the glycosyl hydrolase 2 family. | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | 0.535 |
| EDS74056.1 | EDS74629.1 | CLOSPI_02482 | CLOSPI_01684 | Glycosyl hydrolase family 2, sugar binding domain protein; KEGG: cpf:CPF_1474 0. lacZ; beta-galactosidase K01190; COG: COG3250 Beta-galactosidase/beta-glucuronidase; Psort location: Extracellular, score: 8.07; Belongs to the glycosyl hydrolase 2 family. | Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.446 |
| EDS74629.1 | EDS73995.1 | CLOSPI_01684 | CLOSPI_02421 | Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | 0.577 |
| EDS74629.1 | EDS74056.1 | CLOSPI_01684 | CLOSPI_02482 | Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Glycosyl hydrolase family 2, sugar binding domain protein; KEGG: cpf:CPF_1474 0. lacZ; beta-galactosidase K01190; COG: COG3250 Beta-galactosidase/beta-glucuronidase; Psort location: Extracellular, score: 8.07; Belongs to the glycosyl hydrolase 2 family. | 0.446 |
| EDS74629.1 | EDS75723.1 | CLOSPI_01684 | CLOSPI_00233 | Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Aldehyde dehydrogenase (NAD) family protein; KEGG: ctc:CTC02523 8.9e-108 ywdH; putative aldehyde dehydrogenase YwdH K00128; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98. | 0.910 |
| EDS74629.1 | lysS | CLOSPI_01684 | CLOSPI_02465 | Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | lysine--tRNA ligase; KEGG: gka:GK0074 3.2e-167 lysyl-tRNA synthetase (lysine--tRNA ligase) K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.432 |
| EDS74705.1 | EDS73995.1 | CLOSPI_01482 | CLOSPI_02421 | Hypothetical protein; KEGG: hit:NTHI1634 2.3e-14 NAD-dependent deacetylase sirtuin 5 K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family. | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | 0.533 |
| EDS75394.1 | EDS73995.1 | CLOSPI_00788 | CLOSPI_02421 | DegT/DnrJ/EryC1/StrS aminotransferase family protein; KEGG: cno:NT01CX_1463 6.9e-101 spsC; spore coat polysaccharide biosynthesis protein SpsC K01726; COG: COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87; Belongs to the DegT/DnrJ/EryC1 family. | Oxidoreductase, NAD-binding domain protein; KEGG: lpl:lp_2604 1.7e-81 oxidoreductase; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score: 8.87. | 0.787 |