STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manAKEGG: cno:NT01CX_1588 2.0e-62 manA; mannose-6-phosphate isomerase, class I K01809; COG: COG1482 Phosphomannose isomerase; Psort location: Cytoplasmic, score: 8.87. (321 aa)    
Predicted Functional Partners:
EDS75491.1
Hypothetical protein; KEGG: sha:SH0521 2.0e-10 ptsG; phosphotransferase system enzyme II K02777:K02778:K02779; COG: COG2190 Phosphotransferase system IIA components.
    
 0.916
EDS73779.1
KEGG: sar:SAR0235 1.9e-137 putative PTS transport system, IIBC component K02790:K02791; COG: COG1264 Phosphotransferase system IIB components; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.916
EDS75411.1
ROK family protein; KEGG: bha:BH0797 1.7e-58 glucose kinase K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.905
EDS74631.1
ROK family protein; KEGG: bha:BH0797 1.7e-58 glucose kinase K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.905
nagE
KEGG: sgl:SG0859 6.9e-140 PTS system N-acetylglucosamine-specific IIABC component K02802:K02803:K02804; COG: COG2190 Phosphotransferase system IIA components; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.874
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.858
EDS75804.1
KEGG: efa:EF0020 4.3e-131 PTS system, mannose-specific IIAB components K02793:K02794; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: Cytoplasmic, score: 9.98.
    
 0.836
EDS73783.1
KEGG: efa:EF0020 4.3e-131 PTS system, mannose-specific IIAB components K02793:K02794; COG: COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; Psort location: Cytoplasmic, score: 9.98.
    
 0.836
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.781
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.781
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.