Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppk1Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (676 aa)    
Predicted Functional Partners:
EDS74588.1
DHHA2 domain protein; KEGG: cpe:CPE2055 1.0e-152 probable manganase-dependent inorganic pyrophosphatase K01507; COG: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; Psort location: Cytoplasmic, score: 8.87.
    
  0.901
EDS75989.1
Hypothetical protein; KEGG: fnu:FN0099 4.8e-22 inorganic pyrophosphatase K01507; COG: COG0221 Inorganic pyrophosphatase.
     
  0.900
EDS74054.1
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
     
 0.705
EDS74053.1
Hypothetical protein; KEGG: mhp:MHP7448_0622 0.00027 dam; DNA adenine methylase K06223; COG: KOG0946 ER-Golgi vesicle-tethering protein p115.
       0.674
EDS73746.1
Phospholipase D domain protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
  
  
 0.651
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: gka:GK0265 2.7e-106 phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: CytoplasmicMembrane, score: 7.80.
    
 0.440
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
      0.432
EDS74056.1
Glycosyl hydrolase family 2, sugar binding domain protein; KEGG: cpf:CPF_1474 0. lacZ; beta-galactosidase K01190; COG: COG3250 Beta-galactosidase/beta-glucuronidase; Psort location: Extracellular, score: 8.07; Belongs to the glycosyl hydrolase 2 family.
     
 0.410
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
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