Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS74070.1Cell envelope-like function transcriptional attenuator common domain protein; COG: COG1316 Transcriptional regulator; Psort location: CytoplasmicMembrane, score: 7.63. (497 aa)    
Predicted Functional Partners:
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
     0.656
srtB
Sortase, SrtB family; COG: COG4509 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
     0.583
EDS74071.1
O-antigen polymerase; KEGG: sdy:SDY_4054 2.7e-06 waaL; lipid A-core:surface polymer ligase WaaL K02847; COG: NOG36355 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
    0.580
ychF
GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
       0.515
EDS75394.1
DegT/DnrJ/EryC1/StrS aminotransferase family protein; KEGG: cno:NT01CX_1463 6.9e-101 spsC; spore coat polysaccharide biosynthesis protein SpsC K01726; COG: COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Psort location: Cytoplasmic, score: 8.87; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.459
EDS73991.1
R3H domain protein; COG: COG1847 Predicted RNA-binding protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.437
EDS73950.1
KEGG: bce:BC0896 1.3e-31 S-layer protein / peptidoglycan endo-beta-N-acetylglucosaminidase K01238; COG: COG5263 FOG: Glucan-binding domain (YG repeat); Psort location: Extracellular, score: 9.04.
  
     0.400
Your Current Organism:
Clostridium spiroforme
NCBI taxonomy Id: 428126
Other names: Clostridium spiroforme ATCC 29900, [. spiroforme DSM 1552, [Clostridium] spiroforme DSM 1552
Server load: low (12%) [HD]