STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP12331.1Putative permease; KEGG: bcz:BCZK0244 3.7e-109 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2252 Permeases; Psort location: CytoplasmicMembrane, score:9.99. (450 aa)    
Predicted Functional Partners:
EDP11683.1
Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score:8.87.
  
  
 0.832
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.779
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.754
purM
Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: bha:BH0631 8.9e-108 purM; phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score:8.87.
  
  
 0.622
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
  
 0.601
pdxB
4-phosphoerythronate dehydrogenase; KEGG: btk:BT9727_3022 1.0e-106 serA; D-3-phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.568
EDP12329.1
Aminotransferase, class I/II; KEGG: bce:BC2896 2.8e-95 aspartate aminotransferase; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:8.87.
  
    0.554
guaA-2
GMP synthase (glutamine-hydrolyzing) domain protein; KEGG: bth:BT2419 8.9e-179 putative GMP synthase [glutamine-hydrolyzing] K01951; COG: COG0518 GMP synthase - Glutamine amidotransferase domain; Psort location: Cytoplasmic, score:8.87.
     
 0.550
purC
KEGG: sat:SYN_00107 6.3e-75 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Psort location: Cytoplasmic, score:8.87; Belongs to the SAICAR synthetase family.
  
  
 0.543
EDP12330.1
Peptidase family S51; KEGG: tte:TTE2723 7.6e-31 pepE; peptidase E K05995; COG: COG3340 Peptidase E; Psort location: Cytoplasmic, score:8.87; Belongs to the peptidase S51 family.
       0.513
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.