STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pyrKOxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (253 aa)    
Predicted Functional Partners:
pyrC
Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.999
pyrD
Dihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
 0.999
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.997
carB
Carbamoyl-phosphate synthase, large subunit; KEGG: bcz:BCZK3645 0. carB; carbamoyl-phosphate synthase K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score:8.87; Belongs to the CarB family.
  
 0.992
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.992
pyrB
KEGG: gka:GK1149 1.0e-81 pyrB; aspartate carbamoyltransferase K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score:9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.988
carA
KEGG: bsu:BG10715 1.3e-99 pyrAA; carbamoyl-phosphate synthase small chain K01956; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score:8.87; Belongs to the CarA family.
  
 
 0.983
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score:8.87.
  
 
 0.980
gltA
KEGG: tte:TTE0693 8.6e-158 gltD2; NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score:9.98.
 
 0.974
EDP10741.1
Oxidoreductase, aldo/keto reductase family protein; KEGG: mma:MM3156 8.7e-78 oxidoreductase; COG: COG1453 Predicted oxidoreductases of the aldo/keto reductase family; Psort location: Cytoplasmic, score:8.87.
  
  0.824
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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