STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP12053.1FemAB family protein; KEGG: spj:MGAS2096_Spy0979 1.7e-17 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase / UDP-N-acetylmuramoylpentapeptide-lysine N(6)-seryltransferase K00687:K05363; COG: COG2348 Uncharacterized protein involved in methicillin resistance; Psort location: Cytoplasmic, score:8.87. (422 aa)    
Predicted Functional Partners:
tsaD
Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
     
 0.715
rex
CoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
    0.715
EDP11479.1
FemAB family protein; KEGG: sph:MGAS10270_Spy1034 2.2e-81 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase / UDP-N-acetylmuramoylpentapeptide-lysine N(6)-seryltransferase K00687:K05363; COG: COG2348 Uncharacterized protein involved in methicillin resistance; Psort location: Cytoplasmic, score:8.87.
 
  
0.707
yeaZ
Universal bacterial protein YeaZ; KEGG: sab:SAB1936c 4.5e-17 probable glycoprotein endopeptidase K01409; COG: COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; Psort location: Cytoplasmic, score:8.87.
       0.706
EDP12054.1
Hydrolase, P-loop family; KEGG: cjk:jk1734 1.3e-11 alr; hypothetical protein K01775; COG: COG0802 Predicted ATPase or kinase; Psort location: Cytoplasmic, score:8.87.
       0.699
rimI
Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
       0.694
EDP11191.1
Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.1e-68 probable UDP-N-acetylmuramyl tripeptide synthase K01924; COG: COG0769 UDP-N-acetylmuramyl tripeptide synthase.
 
 
 0.603
murG
Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
   
 
 0.600
EDP11189.1
CobB/CobQ-like protein; KEGG: lsl:LSL_0587 1.2e-39 cobyric acid synthase K01957; COG: COG3442 Predicted glutamine amidotransferase; Psort location: Cytoplasmic, score:8.87.
  
  
  0.544
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
  
 
 0.534
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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