STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrRPhosphoribosyl transferase domain protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (169 aa)    
Predicted Functional Partners:
pyrB
KEGG: gka:GK1149 1.0e-81 pyrB; aspartate carbamoyltransferase K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score:9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.996
pyrC
Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.978
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.974
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
 0.962
EDP10853.1
Phosphoribulokinase/uridine kinase family protein; KEGG: ctc:CTC00344 2.1e-106 uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score:8.87.
    
 0.944
EDP10862.1
Putative permease; KEGG: bcz:BCZK0244 2.3e-06 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; COG: COG2233 Xanthine/uracil permeases; Psort location: CytoplasmicMembrane, score:10.00.
  
  
 0.943
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
 0.927
pdp
KEGG: bld:BLi04227 6.4e-121 pdp; pyrimidine-nucleoside phosphorylase; RBL03695 K00756; COG: COG0213 Thymidine phosphorylase; Psort location: Cytoplasmic, score:8.87.
     
 0.922
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.856
pyrD
Dihydroorotate oxidase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.852
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.