STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP11912.1Hypothetical protein; KEGG: reh:H16_A2563 8.7e-05 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. (65 aa)    
Predicted Functional Partners:
EDP11914.1
Hypothetical protein; COG: COG5660 Predicted integral membrane protein; Psort location: Cytoplasmic, score:8.87.
 
 
 0.928
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.823
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.820
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.809
prkC
Serine/threonine-protein kinase PrkC; KEGG: lsa:LSA0692 1.5e-91 putative serine/threonine protein kinase K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: CytoplasmicMembrane, score:9.49.
   
 
 0.726
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.671
EDP10816.1
Hypothetical protein; KEGG: cca:CCA00778 0.0075 glycerol-serine phosphatidyltransferase, putative K00998; COG: COG4709 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:9.97.
  
 0.651
EDP11913.1
Sigma-70, region 4; Psort location: Cytoplasmic, score:8.87.
       0.642
EDP11910.1
Hypothetical protein; Psort location: Extracellular, score:8.82.
       0.541
EDP12229.1
COG: COG3210 Large exoproteins involved in heme utilization or adhesion; Psort location: Cytoplasmic, score:8.87.
    
  0.493
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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