STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP11949.1Hypothetical protein; KEGG: tbd:Tbd_2668 4.4e-16 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:9.99. (380 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.738
EDP11951.1
Peptidase, S41 family; KEGG: bsu:BG11794 1.1e-59 ctpA, yzbD; carboxy-terminal processing protease K03797; COG: COG0793 Periplasmic protease; Psort location: Cytoplasmic, score:8.87; Belongs to the peptidase S41A family.
       0.731
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
    
  0.492
EDP10471.1
Putative sporulation integral membrane protein YtvI; KEGG: tbd:Tbd_2668 1.1e-11 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:9.99.
  
     0.465
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
  
    0.435
EDP11952.1
Efflux ABC transporter, permease protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.432
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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