STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP11568.1Hypothetical protein; COG: NOG13728 non supervised orthologous group; Psort location: Cytoplasmic, score:8.87. (365 aa)    
Predicted Functional Partners:
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.779
EDP11569.1
ThiF family protein; KEGG: cal:orf19.2115 1.0e-28 molybdopterin-converting factor; COG: COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1; Psort location: Cytoplasmic, score:8.87.
       0.773
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.773
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.756
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.737
EDP11573.1
Hypothetical protein; COG: COG2801 Transposase and inactivated derivatives.
 
     0.666
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
 
 0.658
pyk
Pyruvate kinase; KEGG: bce:BC4599 1.3e-131 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.87.
    
   0.655
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.655
EDP10964.1
Cation diffusion facilitator family transporter; KEGG: cal:orf19.2410 9.3e-11 IMH1; involved in vesicular transport K01553; COG: NOG16864 non supervised orthologous group.
  
     0.556
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.