STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKNAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (256 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; KEGG: tte:TTE0640 9.4e-49 nadE; NAD synthase K01950; COG: COG0388 Predicted amidohydrolase; Belongs to the NAD synthetase family.
    
 0.971
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.963
cobB
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
 0.930
EDP11656.1
Acetyltransferase, GNAT family; KEGG: lma:LmjF28.3005 3.1e-05 glucose 6-phosphate N-acetyltransferase, putative K00621; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score:8.87.
  
    0.748
EDP10143.1
Hydrolase, NUDIX family; KEGG: cno:NT01CX_0807 2.0e-14 MutT/NUDIX family protein, putative K01529; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
     
 0.744
EDP11357.1
Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.
 
 
 0.704
EDP11202.1
KEGG: cff:CFF8240_1111 3.2e-23 rrmJ; ribosomal RNA large subunit methyltransferase J K00599; COG: COG1189 Predicted rRNA methylase; Psort location: Cytoplasmic, score:8.87.
  
  
 0.670
EDP11654.1
Adenylate cyclase; KEGG: sar:SAR0971 3.6e-17 glutathione S-transferase K00799; COG: COG4116 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.87.
 
     0.664
EDP10614.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: afu:AF1262 3.5e-97 noxB-2; NADH oxidase (NoxB-2) K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score:8.87.
  
 
 0.621
EDP10615.1
NADH oxidase; KEGG: afu:AF1262 8.0e-107 noxB-2; NADH oxidase (NoxB-2) K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score:8.87.
  
 
 0.621
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.