STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP11662.1Redox-active disulfide protein 2; KEGG: fnu:FN1984 0.0049 thioredoxin reductase / glutaredoxin-like protein K00384; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score:8.87. (110 aa)    
Predicted Functional Partners:
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.999
EDP10614.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: afu:AF1262 3.5e-97 noxB-2; NADH oxidase (NoxB-2) K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score:8.87.
  
 0.980
EDP10615.1
NADH oxidase; KEGG: afu:AF1262 8.0e-107 noxB-2; NADH oxidase (NoxB-2) K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score:8.87.
  
 0.980
EDP10467.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.953
EDP11660.1
COG: COG0701 Predicted permeases; Psort location: CytoplasmicMembrane, score:9.99.
 
  
 0.952
EDP11498.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: fnu:FN0182 3.6e-143 sarcosine oxidase alpha subunit K00301; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score:9.98.
  
 0.904
trxB
KEGG: bcl:ABC3038 4.3e-76 trxB; thioredoxin reductase K00384; COG: COG0492 Thioredoxin reductase; Psort location: Cytoplasmic, score:9.98.
  
 0.904
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.889
EDP11538.1
LPXTG-motif cell wall anchor domain protein; KEGG: bme:BMEII0148 5.9e-10 extracellular serine protease; COG: COG3468 Type V secretory pathway, adhesin AidA; Psort location: Cellwall, score:9.91.
    
 0.887
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 0.887
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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