STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP11780.1Recombination factor protein RarA; KEGG: ava:Ava_B0112 1.9e-66 ATPase K00961:K07478; COG: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; Psort location: Cytoplasmic, score:8.87. (429 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 
 0.820
nadE
NAD+ synthase; KEGG: tte:TTE0640 9.4e-49 nadE; NAD synthase K01950; COG: COG0388 Predicted amidohydrolase; Belongs to the NAD synthetase family.
  
    0.714
EDP11350.1
FtsK/SpoIIIE family protein; KEGG: pen:PSEEN2212 8.8e-101 ftsK; cell division protein FtsK; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score:9.99; Belongs to the FtsK/SpoIIIE/SftA family.
  
 0.687
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
       0.682
EDP11501.1
HAD hydrolase, family IIA; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family.
 
      0.660
EDP10398.1
Hypothetical protein; KEGG: lwe:lwe1660 6.4e-114 DNA/RNA helicase protein K01529; COG: COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Psort location: Cytoplasmic, score:8.87.
  
 
 0.645
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.591
EDP11778.1
Stress responsive A/B barrel domain protein; COG: NOG17822 non supervised orthologous group.
       0.590
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
   0.539
EDP10208.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: gka:GK3297 6.1e-148 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score:8.87.
   
   0.539
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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