node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDP11040.1 | EDP11540.1 | EUBDOL_01368 | EUBDOL_00718 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | 0.974 |
EDP11040.1 | hisA | EUBDOL_01368 | EUBDOL_01371 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | KEGG: cno:NT01CX_1065 2.6e-62 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814; COG: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Psort location: Cytoplasmic, score:9.65. | 0.992 |
EDP11040.1 | hisB | EUBDOL_01368 | EUBDOL_01369 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | KEGG: cno:NT01CX_1064 1.6e-53 imidazoleglycerol-phosphate dehydratase (IGPD) K01693; COG: COG0131 Imidazoleglycerol-phosphate dehydratase; Psort location: Cytoplasmic, score:8.87. | 0.999 |
EDP11040.1 | hisD | EUBDOL_01368 | EUBDOL_01367 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.999 |
EDP11040.1 | hisE | EUBDOL_01368 | EUBDOL_01374 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | KEGG: cac:CAC0943 7.3e-26 his_2; phosphoribosyl-ATP pyrophosphohydrolase K01523; COG: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; Psort location: Cytoplasmic, score:9.98. | 0.950 |
EDP11040.1 | hisF | EUBDOL_01368 | EUBDOL_01372 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.997 |
EDP11040.1 | hisG | EUBDOL_01368 | EUBDOL_01366 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.990 |
EDP11040.1 | hisH | EUBDOL_01368 | EUBDOL_01370 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.997 |
EDP11040.1 | hisI | EUBDOL_01368 | EUBDOL_01373 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.994 |
EDP11040.1 | hisZ | EUBDOL_01368 | EUBDOL_01365 | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | Putative ATP phosphoribosyltransferase, regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.942 |
EDP11540.1 | EDP11040.1 | EUBDOL_00718 | EUBDOL_01368 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.974 |
EDP11540.1 | hisA | EUBDOL_00718 | EUBDOL_01371 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | KEGG: cno:NT01CX_1065 2.6e-62 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814; COG: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Psort location: Cytoplasmic, score:9.65. | 0.615 |
EDP11540.1 | hisB | EUBDOL_00718 | EUBDOL_01369 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | KEGG: cno:NT01CX_1064 1.6e-53 imidazoleglycerol-phosphate dehydratase (IGPD) K01693; COG: COG0131 Imidazoleglycerol-phosphate dehydratase; Psort location: Cytoplasmic, score:8.87. | 0.955 |
EDP11540.1 | hisD | EUBDOL_00718 | EUBDOL_01367 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.617 |
EDP11540.1 | hisF | EUBDOL_00718 | EUBDOL_01372 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.665 |
EDP11540.1 | hisG | EUBDOL_00718 | EUBDOL_01366 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.617 |
EDP11540.1 | hisH | EUBDOL_00718 | EUBDOL_01370 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.516 |
EDP11540.1 | hisI | EUBDOL_00718 | EUBDOL_01373 | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.501 |
hisA | EDP11040.1 | EUBDOL_01371 | EUBDOL_01368 | KEGG: cno:NT01CX_1065 2.6e-62 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814; COG: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Psort location: Cytoplasmic, score:9.65. | Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. | 0.992 |
hisA | EDP11540.1 | EUBDOL_01371 | EUBDOL_00718 | KEGG: cno:NT01CX_1065 2.6e-62 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814; COG: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Psort location: Cytoplasmic, score:9.65. | Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. | 0.615 |