node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDP10656.1 | EDP10658.1 | EUBDOL_01914 | EUBDOL_01916 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Hypothetical protein; COG: NOG11764 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.99. | 0.732 |
EDP10656.1 | EDP11048.1 | EUBDOL_01914 | EUBDOL_01376 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Oxidoreductase, aldo/keto reductase family protein; KEGG: lsa:LSA0238 3.8e-61 putative aldo/keto reductase (oxidoreductase) K00100; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase; Psort location: Cytoplasmic, score:8.87. | 0.648 |
EDP10656.1 | EDP11357.1 | EUBDOL_01914 | EUBDOL_01277 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | 0.691 |
EDP10656.1 | EDP12284.1 | EUBDOL_01914 | EUBDOL_00193 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Hydrolase, alpha/beta domain protein; KEGG: mtu:Rv2715 3.0e-19 possible hydrolase; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: Cytoplasmic, score:8.87. | 0.625 |
EDP10656.1 | cobB | EUBDOL_01914 | EUBDOL_01925 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.628 |
EDP10656.1 | nadD | EUBDOL_01914 | EUBDOL_01292 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.820 |
EDP10656.1 | nadE | EUBDOL_01914 | EUBDOL_01483 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | NAD+ synthase; KEGG: tte:TTE0640 9.4e-49 nadE; NAD synthase K01950; COG: COG0388 Predicted amidohydrolase; Belongs to the NAD synthetase family. | 0.723 |
EDP10656.1 | nagB | EUBDOL_01914 | EUBDOL_00088 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.660 |
EDP10656.1 | nnrE | EUBDOL_01914 | EUBDOL_01677 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.636 |
EDP10656.1 | pncB | EUBDOL_01914 | EUBDOL_01915 | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.906 |
EDP10658.1 | EDP10656.1 | EUBDOL_01916 | EUBDOL_01914 | Hypothetical protein; COG: NOG11764 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.99. | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | 0.732 |
EDP10658.1 | pncB | EUBDOL_01916 | EUBDOL_01915 | Hypothetical protein; COG: NOG11764 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.99. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.782 |
EDP11048.1 | EDP10656.1 | EUBDOL_01376 | EUBDOL_01914 | Oxidoreductase, aldo/keto reductase family protein; KEGG: lsa:LSA0238 3.8e-61 putative aldo/keto reductase (oxidoreductase) K00100; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase; Psort location: Cytoplasmic, score:8.87. | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | 0.648 |
EDP11048.1 | EDP12284.1 | EUBDOL_01376 | EUBDOL_00193 | Oxidoreductase, aldo/keto reductase family protein; KEGG: lsa:LSA0238 3.8e-61 putative aldo/keto reductase (oxidoreductase) K00100; COG: COG0656 Aldo/keto reductases, related to diketogulonate reductase; Psort location: Cytoplasmic, score:8.87. | Hydrolase, alpha/beta domain protein; KEGG: mtu:Rv2715 3.0e-19 possible hydrolase; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: Cytoplasmic, score:8.87. | 0.619 |
EDP11357.1 | EDP10656.1 | EUBDOL_01277 | EUBDOL_01914 | Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87. | 0.691 |
EDP11357.1 | EDP12284.1 | EUBDOL_01277 | EUBDOL_00193 | Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Hydrolase, alpha/beta domain protein; KEGG: mtu:Rv2715 3.0e-19 possible hydrolase; COG: COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Psort location: Cytoplasmic, score:8.87. | 0.930 |
EDP11357.1 | cobB | EUBDOL_01277 | EUBDOL_01925 | Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.719 |
EDP11357.1 | nadD | EUBDOL_01277 | EUBDOL_01292 | Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.984 |
EDP11357.1 | nadE | EUBDOL_01277 | EUBDOL_01483 | Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | NAD+ synthase; KEGG: tte:TTE0640 9.4e-49 nadE; NAD synthase K01950; COG: COG0388 Predicted amidohydrolase; Belongs to the NAD synthetase family. | 0.971 |
EDP11357.1 | pncB | EUBDOL_01277 | EUBDOL_01915 | Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.969 |