STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (493 aa)    
Predicted Functional Partners:
EDP11357.1
Competence/damage-inducible domain protein CinA; COG: COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.
  
 
 0.969
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.966
deoD
KEGG: msy:MS53_0447 1.9e-59 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score:8.87.
     
 0.918
EDP10656.1
Hypothetical protein; KEGG: mka:MK0504 1.1e-08 amidase related to nicotinamidase K01440; COG: COG1335 Amidases related to nicotinamidase; Psort location: Cytoplasmic, score:8.87.
  
 
 0.906
nadE
NAD+ synthase; KEGG: tte:TTE0640 9.4e-49 nadE; NAD synthase K01950; COG: COG0388 Predicted amidohydrolase; Belongs to the NAD synthetase family.
 
 
 0.901
EDP10143.1
Hydrolase, NUDIX family; KEGG: cno:NT01CX_0807 2.0e-14 MutT/NUDIX family protein, putative K01529; COG: COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
    
 0.786
EDP10658.1
Hypothetical protein; COG: NOG11764 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.99.
       0.782
nifJ
KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score:8.87.
     
 0.750
cobB
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 0.659
EDP10294.1
Bacterial capsule synthesis protein; KEGG: tte:TTE0343 0.0062 ushA; 5-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases' K01119; COG: COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation).
  
    0.652
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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