STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP10280.1COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score:8.87; Belongs to the sigma-70 factor family. (193 aa)    
Predicted Functional Partners:
mrnC
RNase3 domain protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
    0.831
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.823
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.820
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.809
EDP10279.1
RNA methyltransferase, TrmH family, group 3; KEGG: bha:BH0113 1.4e-54 tRNA/rRNA methyltransferase K03218; COG: COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
  
    0.789
cysS
cysteine--tRNA ligase; KEGG: gka:GK0085 2.4e-105 cysteinyl-tRNA synthetase K01883; COG: COG0215 Cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score:9.98; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.772
prkC
Serine/threonine-protein kinase PrkC; KEGG: lsa:LSA0692 1.5e-91 putative serine/threonine protein kinase K08884; COG: COG0515 Serine/threonine protein kinase; Psort location: CytoplasmicMembrane, score:9.49.
   
 
 0.726
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.671
EDP10816.1
Hypothetical protein; KEGG: cca:CCA00778 0.0075 glycerol-serine phosphatidyltransferase, putative K00998; COG: COG4709 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:9.97.
  
 0.651
EDP10286.1
Putative HAD hydrolase, TIGR01457 family; KEGG: fnu:FN0048 6.7e-71 4-nitrophenylphosphatase K01101; COG: COG0647 Predicted sugar phosphatases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87.
  
    0.560
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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