STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP10294.1Bacterial capsule synthesis protein; KEGG: tte:TTE0343 0.0062 ushA; 5-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases' K01119; COG: COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation). (374 aa)    
Predicted Functional Partners:
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
       0.785
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.744
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
  
    0.652
EDP11098.1
Serine-type D-Ala-D-Ala carboxypeptidase; KEGG: bcz:BCZK1351 1.9e-57 dacB; D-alanyl-D-alanine carboxypeptidase K01286; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Psort location: Cytoplasmic, score:8.87; Belongs to the peptidase S11 family.
 
      0.620
secG
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
    0.590
EDP11191.1
Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.1e-68 probable UDP-N-acetylmuramyl tripeptide synthase K01924; COG: COG0769 UDP-N-acetylmuramyl tripeptide synthase.
    
 0.519
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
    
 0.511
murE-2
KEGG: bha:BH2571 3.3e-62 murE; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate ligase K01928; COG: COG0769 UDP-N-acetylmuramyl tripeptide synthase; Belongs to the MurCDEF family. MurE subfamily.
    
 0.511
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
  0.504
EDP12285.1
Mur ligase middle domain protein; KEGG: tte:TTE2546 8.7e-78 murF; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase K01929; COG: COG0770 UDP-N-acetylmuramyl pentapeptide synthase.
    
  0.498
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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