STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuKu protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (304 aa)    
Predicted Functional Partners:
ACS61794.1
TIGRFAM: DNA ligase D; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; DNA primase small subunit; KEGG: psb:Psyr_3245 ATP-dependent DNA ligase.
 
  
 0.990
ACS64689.1
KEGG: pmy:Pmen_2775 DNA topoisomerase.
 
    0.735
ACS65076.1
KEGG: bxe:Bxe_A2030 hypothetical protein.
 
     0.583
ACS61796.1
PFAM: major facilitator superfamily MFS_1; KEGG: rso:RSc0585 putative transport transmembrane protein.
       0.499
ACS64550.1
KEGG: bpt:Bpet1645 putative secreted protein.
 
    0.489
ACS61792.1
TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin-guanine dinucleotide biosynthesis MobB region; KEGG: rso:RSc0583 molybdopterin-guanine dinucleotide biosynthesis protein B.
       0.459
ACS61793.1
KEGG: rso:RSc0584 D-alanyl-D-alanine carboxypeptidase; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C.
       0.459
ACS65300.1
Trehalose synthase; KEGG: rso:RS05183 hypothetical protein; TIGRFAM: trehalose synthase; trehalose synthase-fused possible maltokinase; PFAM: alpha amylase catalytic region; aminoglycoside phosphotransferase; SMART: alpha amylase catalytic sub domain.
 
    0.458
ACS65077.1
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: azo:azo1732 short-chain dehydrogenase family protein.
  
     0.444
ACS61388.1
PFAM: Hemerythrin HHE cation binding domain protein; KEGG: azo:azo0331 hypothetical protein.
 
     0.423
Your Current Organism:
Ralstonia pickettii 12D
NCBI taxonomy Id: 428406
Other names: R. pickettii 12D, Ralstonia pickettii str. 12D, Ralstonia pickettii strain 12D
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