STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS63012.1TIGRFAM: propionate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RSc1518 propionyl-CoA synthetase. (633 aa)    
Predicted Functional Partners:
ACS65230.1
KEGG: rso:RSp0121 methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.941
ACS65337.1
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: rso:RSp0650 methylmalonate-semialdehyde dehydrogenase oxidoreductase protein.
   
 0.923
ACS65627.1
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: rso:RS02392 transmembrane aldehyde dehydrogenase oxidoreductase protein.
   
 0.923
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.923
ACS64828.1
PFAM: AMP-dependent synthetase and ligase; KEGG: bte:BTH_II0927 acetyl-CoA synthetase.
  
  
 
0.922
ACS65336.1
PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS05571 acetyl-coenzyme A synthetase.
  
  
 
0.922
ACS65500.1
PFAM: AMP-dependent synthetase and ligase; KEGG: rso:RS05310 acetyl-coenzyme A synthetase.
  
  
 
0.922
ACS61442.1
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: rso:RSc0274 putative acyl CoA dehydrogenase oxidoreductase protein.
  
 
  0.916
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.911
ACS61667.1
Coenzyme A transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
     
 0.906
Your Current Organism:
Ralstonia pickettii 12D
NCBI taxonomy Id: 428406
Other names: R. pickettii 12D, Ralstonia pickettii str. 12D, Ralstonia pickettii strain 12D
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