STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
Experiments
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[Homology]
Score
ACS63206.1Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (345 aa)    
Predicted Functional Partners:
ACS63204.1
KEGG: rso:RSc2096 xanthine dehydrogenase subunit B; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead.
 
  
 0.983
ACS63203.1
TIGRFAM: xanthine dehydrogenase, small subunit; PFAM: molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; ferredoxin; KEGG: rso:RSc2095 putative xanthine dehydrogenase (subunit A) oxidoreductase protein.
 
  
 0.979
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.957
ACS63918.1
PFAM: phosphoribosyltransferase; KEGG: rso:RSc2812 hypoxanthine-guanine phosphoribosyltransferase.
     
 0.930
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
 
 
 0.924
ppnP
Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.903
ACS64297.1
PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; KEGG: cti:RALTA_B0901 xanthine dehydrogenase, with FAD-binding domain.
    
  0.903
ACS64296.1
PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; KEGG: bph:Bphy_4727 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
    
  0.902
ACS64298.1
PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: bxe:Bxe_B2224 2Fe-2S ferredoxin.
    
  0.902
ACS63207.1
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
 
 
 0.848
Your Current Organism:
Ralstonia pickettii 12D
NCBI taxonomy Id: 428406
Other names: R. pickettii 12D, Ralstonia pickettii str. 12D, Ralstonia pickettii strain 12D
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