node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS62319.1 | ftsQ | Rpic12D_1020 | Rpic12D_2721 | Hypothetical protein; KEGG: aau:AAur_1713 cell division protein FtsZ. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.514 |
ACS62319.1 | zapD | Rpic12D_1020 | Rpic12D_2709 | Hypothetical protein; KEGG: aau:AAur_1713 cell division protein FtsZ. | Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.719 |
ACS62640.1 | ACS64614.1 | Rpic12D_1351 | Rpic12D_3350 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: rso:RSc1413 hypothetical protein; Belongs to the skp family. | KEGG: rso:RSc0076 proline rich signal peptide protein. | 0.540 |
ACS62640.1 | lptE | Rpic12D_1351 | Rpic12D_2572 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: rso:RSc1413 hypothetical protein; Belongs to the skp family. | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. | 0.477 |
ACS62640.1 | zapD | Rpic12D_1351 | Rpic12D_2709 | PFAM: outer membrane chaperone Skp (OmpH); KEGG: rso:RSc1413 hypothetical protein; Belongs to the skp family. | Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.581 |
ACS63015.1 | ftsQ | Rpic12D_1732 | Rpic12D_2721 | PFAM: Methyltransferase type 11; KEGG: rso:RSc1514 hypothetical protein. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.428 |
ACS63015.1 | lptE | Rpic12D_1732 | Rpic12D_2572 | PFAM: Methyltransferase type 11; KEGG: rso:RSc1514 hypothetical protein. | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. | 0.612 |
ACS63015.1 | zapD | Rpic12D_1732 | Rpic12D_2709 | PFAM: Methyltransferase type 11; KEGG: rso:RSc1514 hypothetical protein. | Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.618 |
ACS63978.1 | coaE | Rpic12D_2707 | Rpic12D_2708 | Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.866 |
ACS63978.1 | yacG | Rpic12D_2707 | Rpic12D_2710 | Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.529 |
ACS63978.1 | zapD | Rpic12D_2707 | Rpic12D_2709 | Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.617 |
ACS64614.1 | ACS62640.1 | Rpic12D_3350 | Rpic12D_1351 | KEGG: rso:RSc0076 proline rich signal peptide protein. | PFAM: outer membrane chaperone Skp (OmpH); KEGG: rso:RSc1413 hypothetical protein; Belongs to the skp family. | 0.540 |
ACS64614.1 | ftsQ | Rpic12D_3350 | Rpic12D_2721 | KEGG: rso:RSc0076 proline rich signal peptide protein. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.679 |
ACS64614.1 | lptE | Rpic12D_3350 | Rpic12D_2572 | KEGG: rso:RSc0076 proline rich signal peptide protein. | Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family. | 0.658 |
ACS64614.1 | zapD | Rpic12D_3350 | Rpic12D_2709 | KEGG: rso:RSc0076 proline rich signal peptide protein. | Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.674 |
coaE | ACS63978.1 | Rpic12D_2708 | Rpic12D_2707 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.866 |
coaE | yacG | Rpic12D_2708 | Rpic12D_2710 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.569 |
coaE | zapD | Rpic12D_2708 | Rpic12D_2709 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.930 |
ftsQ | ACS62319.1 | Rpic12D_2721 | Rpic12D_1020 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Hypothetical protein; KEGG: aau:AAur_1713 cell division protein FtsZ. | 0.514 |
ftsQ | ACS63015.1 | Rpic12D_2721 | Rpic12D_1732 | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | PFAM: Methyltransferase type 11; KEGG: rso:RSc1514 hypothetical protein. | 0.428 |